| Autor: |
Prabhu, T. Purushoth, Parameswari, S. Padma Thanga, Sandhiya, N., Venkatraman, N. Deepak, Sheela, T., Kavitha, C., Shakeel, O. S. Mohamed, Ramanathan, N. |
| Předmět: |
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| Zdroj: |
International Journal of Pharma Research; Jul-Dec2023, Vol. 13 Issue 2, p84-87, 4p |
| Abstrakt: |
Arthritis, an inflammatory joint disease-causing synovial membrane inflammation, pain, and restricted movement, affects approximately 2% of the Indian population. This study systematically explores the synergistic anti-arthritic potential of a combined extract from Boswellia serrata and Melia azedarach. Phytochemical analysis of the extract identified coumarin, alkaloids, flavonoids, polyphenols, and tannins through TLC studies. The anti-arthritic assay, employing the protein denaturation method, determined IC50 values for the combined extract (BS&MA) and the reference standard (Diclofenac sodium) as 594.35µg/ml and 87.12µg/ml, respectively. Comparative analysis indicated moderate anti-arthritic activity for the combined extract in relation to diclofenac sodium. These preliminary findings warrant further in vitro investigations to substantiate and extend our understanding of the observed effects. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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