From Plant To Pill: Investigating Prosopis Juliflora Fruit Mucilage As A Pharmaceutical Excipient Through Isolation And Physicochemical Analysis.

Autor: Kumar, Yamjala Ganesh, Dipali, Talele, Pimpalshende, Pankaj Mohan, Punathil, Rini, Gouthaman, Karthika, Khetre, Akshada Devendra
Zdroj: Journal of Advanced Zoology; 2024, Vol. 45 Issue 2, p1115-1126, 12p
Abstrakt: This study investigates the extraction and characterization of mucilage from Prosopis juliflora fruits as a potential pharmaceutical excipient. Employing water as the extraction medium, two precipitation approaches (Acetone and 95% ethanol) were compared. Physical, chemical, and micrometric analyses, along with FTIR spectroscopy, were conducted on the mucilages, demonstrating their compliance with official pharmaceutical parameters. Notably, mucilage precipitated with acetone exhibited superior characteristics compared to ethanol. The research concludes that Prosopis juliflora fruit mucilage holds promise as a tablet binder and viscosity-modulating agent in pharmaceutical formulations, offering a cost-effective and sustainable alternative for pharmaceutical applications. Further studies, including in vivo testing and stability assessments, are warranted for comprehensive validation of its pharmaceutical utility. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index