| Abstrakt: |
At the Prometheus medical accelerator with a proton beam energy of 225 MeV, a source of fast and epithermal neutrons is constructed and the neutron dose profiles are measured at the output of the neutron channel using the BDMN-100 detector. A heavy NaI target is used to produce fast neutrons. Together with the research laboratory of the Central Laboratory of AO Avangard, a new protective material against neutrons called wikineutron is developed, with a different percentage of 10B. Based on the developed new protective materials against neutrons, a shadow protection is formed, made in the form of surface contacting cones, forming a channel of fast and epithermal neutrons. Fast neutrons can be used for remote therapy. The developed neutron channel can be used for medical work on the creation of new radiopharmaceuticals containing boron and other highly absorbing elements. It is also possible to use a neutron source from the Prometheus accelerator for the treatment of superficial tumors. The main goal of this study is the formation, based on the developed neutron-absorbing materials, of a neutron channel, which has a simple design and can be used for boron neutron capture therapy (BNCT) and supraepithermal therapy, as well as the creation on the neutron channel of a beam of epithermal neutrons and supraepithermal neutrons to assess the effectiveness of the use of radiopharmaceuticals. The developed neutron-absorbing materials make it possible to create a neutron channel of epithermal neutrons and supraepithermal neutrons for therapy and the development of gold-based radiosensitizers. [ABSTRACT FROM AUTHOR] |
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