| Autor: |
ATACAN YAŞGÜÇLÜKAL, Miray, ÖZÇELİK, Emel UR, ELMALI, Ayşe Deniz, ÇOKAR, Özlem, DEMİRBİLEK, Veysi |
| Předmět: |
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| Zdroj: |
Archives of Neuropsychiatry / Nöropsikiyatri Arşivi; Mar2024, Vol. 61 Issue 1, p85-89, 5p |
| Abstrakt: |
Introduction: We aimed to investigate the long-term prognosis of childhood absence epilepsy (CAE), and identify factors associated with treatment outcomes. Methods: Patients with a definitive diagnosis of CAE according to the International League Against Epilepsy 2021 criteria and with a minimum of 3-year follow-up duration were included. The children were divided according to the time of seizure control. Early seizure remission was defined as seizure freedom within 6 months after the treatment onset. Results: Twenty-four patients with a mean age of 13.7 (9.4-22.0) were included in this study. At the final follow-up, all patients were seizure-free except for one case. Seizure freedom was achieved after initial treatment in a mean of 0.78 years. The treatment was ceased in 19 children (79.2%) after a mean of 3.2 years. Patients having absence seizures without motor components had a higher rate of early seizure remission (p=0.026). In 81.3% of the patients; all of whose repetitive post-treatment EEGs were devoid of any generalized spike-wave discharges and absence seizures; remission was established within 6 months or less (p=0.026). Conclusions: CAE has a favorable prognosis with seizure control obtained in the majority of the cases and more than half of them were obtained within 6 months following the initiation of treatment. Moreover, having an absence seizure without motor components and repetitively normal post-treatment EEGs appear to be associated with a higher rate of early seizure remission. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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