ELUCIDATION AND COMPARATIVE ASSESSMENT OF THE PHYTOCHEMICAL CONTENT AND ANTIBACTERIAL ACTIVITY OF PARTHENIUM HYSTEROPHORUS EXTRACT IN DIFFERENT SOLVENTS.

Autor: ABBAS, M., KHAN, A. A., KHAN, T., QADIR, R., AZIZ, T., ALHARBI, M., ALSAHAMMARI, A., ALASMARI, A. F.
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Zdroj: Applied Ecology & Environmental Research; 2024, Vol. 22 Issue 1, p761-775, 15p
Abstrakt: The current study presents a comparative assessment of the phytochemical contents and antibacterial activity of Parthenium hysterophorus in different solvents of varying polarities (n-hexane, acetone, and water). Extraction was carried out using orbital shaker and extracts were tested against selected bacterial strains by applying disc diffusion process. The antioxidant potential of the Parthenium weeds extract was measured in terms of total phenolic contents (TPC), total flavonoid contents (TFC) and diphenyl picrylhydrazyl (DPPH) free radical scavenging activity. The results revealed that aqueous extracts had higher TPC values (151 µg GAE/g) relative to acetone (127 µg GAE/g) and n-hexane (118 µg GAE/g) extracts. Whereas in the case of TFC, the acetone extract exhibited higher values (31 µg QE/g) followed by n-Hexane (26 µg QE/g) and aqueous extract (5 µg QE/g). DPPH scavenging activity was higher in the case of n-Hexane extract followed by acetone and aqueous extracts. The antibacterial potential of the extracts prepared using three different solvents demonstrated that these extracts are capable of resisting bacterial activity and hence cease their function. The most prominent inhibition zones appeared in the case of nhexane extract, whereas the aqueous extract had the lowest potential to inhibit the bacterial function. The results obtained in this current study support that Parthenium weed extracts have significant antioxidant and antibacterial functions and hence can be used as an ingredient in pharmaceuticals. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index