| Autor: |
Emmert, Maximilian Y, Burrello, Jacopo, Wolint, Petra, Hilbe, Monika, Andriolo, Gabriella, Balbi, Carolina, Provasi, Elena, Turchetto, Lucia, Radrizzani, Marina, Nazari-Shafti, Timo Z, Cesarovic, Nikola, Neuber, Sebastian, Falk, Volkmar, Hoerstrup, Simon P, Hemetsberger, Rayyan, Gyöngyösi, Mariann, Barile, Lucio, Vassalli, Giuseppe |
| Předmět: |
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| Zdroj: |
European Heart Journal; 3/1/2024, Vol. 45 Issue 9, p728-732, 5p |
| Abstrakt: |
This article discusses a study that evaluated the potential use of small extracellular vesicles (sEVs) derived from human cardiac progenitor cells (CPCs) for the treatment of acute myocardial infarction (AMI). The study compared the delivery of sEVs through intramyocardial (IM) and intracoronary (IC) routes in a porcine model of AMI. The results showed that IC delivery of sEVs was more effective in reducing scar size, improving heart function, promoting blood vessel growth, and reducing myocardial fibrosis. The study suggests that IC delivery of clinical-grade sEVs could be a promising treatment option for AMI patients, but further research is needed to validate these findings. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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