| Autor: |
Li, Hua, Shi, Qihao, Yang, Yanhua, Qi, Jinghao, Zhang, Yuhan, Wang, Fengyun, Du, Xiaoxia, Xiao, Wenxiang |
| Předmět: |
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| Zdroj: |
Nanotechnology & Precision Engineering; Mar2024, Vol. 7 Issue 1, p1-8, 8p |
| Abstrakt: |
As a promising cancer treatment method, cold atmospheric plasma has received widespread attention in recent years. However, previous research has focused more on how to realize and expand the anti-cancer scope of plasma jet. There are also studies on the killing of small-scale cancer cells, but the effects of plasma jet on normal cells and normal cell clusters have been ignored. Therefore, we proposed a 50 µm sized micro-plasma jet device, and used the device to treat melanoma cells (A-375) and human glial cells (HA1800) to evaluate their anti-cancer effects and effects on normal cells. The experimental results show that this kind of micro-plasma jet device can effectively inactivate cancer cells in a short period of time, while having little effect on normal cells. This work provides a certain experimental basis for the application of fine plasma jet to clinically inactivate cancer cells. ARTICLE HIGHLIGHTS: HIGHLIGHTS • The experiment of apoptosis induced by plasma jet was carried out in this paper. A-375 and HA1800 were treated with plasma jet and subsequently characterized. • Based on the experimental results of this paper, it can be concluded that plasma jet has a significant role in inducing apoptosis. • The ability of plasma jet to induce apoptosis of cancer cells is much higher than that of normal cells. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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