| Abstrakt: |
A recent study conducted by researchers from the Chinese Academy of Sciences has found that a protein called DRAK2 plays a crucial role in impairing pancreatic beta cell function, which can lead to type 2 diabetes. The researchers discovered that DRAK2 is up-regulated in pancreatic tissue in humans, macaques, and mice with type 2 diabetes. Further experiments in mice showed that blocking DRAK2 protected beta cell function and promoted autophagy and mitochondrial function. The study suggests that targeting the DRAK2-ULK1 axis could be a potential strategy to protect beta cell function in type 2 diabetes. [Extracted from the article] |
