Abstrakt: |
A recent study conducted at Erasmus University Medical Center has found that statins, a type of medication commonly used to lower cholesterol, may prevent the negative effects of placental chemerin upregulation in preeclampsia. Preeclampsia is a condition that affects pregnant women and is characterized by high blood pressure and damage to organs such as the liver and kidneys. The study found that chemerin, an inflammatory protein, is elevated in women with preeclampsia, and its addition to a predictive model improved the accuracy of predicting preeclampsia and its complications. Statins were also found to reverse the release of chemerin and other proteins associated with preeclampsia in placentas and placental explants. The researchers suggest that statins may offer a potential mechanism for preventing or treating preeclampsia. [Extracted from the article] |