Abstrakt: |
A recent study conducted by researchers at the Walter and Eliza Hall Institute of Medical Research in Australia has found that individuals with coeliac disease (CD) often have impaired IgM memory B cell function, which can lead to increased susceptibility to serious pneumococcal infection. The study also examined the effectiveness of different pneumococcal vaccines in inducing protective immune responses. The researchers concluded that pneumococcal vaccination, particularly with a conjugate vaccine, should be recommended for all CD patients as a routine practice. The findings suggest that current clinical tests may not detect functional B cell defects in CD, highlighting the need for improved screening approaches. [Extracted from the article] |