| Abstrakt: |
A recent report from researchers at the Universidad de Malaga in Spain explores the relationship between hydrocephalus and agenesis of the corpus callosum, two neurodevelopmental disorders that often coexist. The study focuses on the hyh mouse model for congenital hydrocephalus, which also develops agenesis of the corpus callosum. The researchers found that a defective program in the development of neuroepithelium affects the glial wedge cells, which are necessary for guiding pioneering axons. This defect in the glial wedge cells causes the axons to turn toward the ipsilateral lateral ventricle, leading to hydrocephalus. The study suggests that further research is needed to understand the etiology of corpus callosum dysgenesis when it occurs with hydrocephalus. [Extracted from the article] |
