Abstrakt: |
Researchers at Ohio State University have developed a new method to enhance the therapeutic potential of adipose stem cells (ASCs) for tissue regeneration. The researchers used lipid nanoparticles to reprogram ASCs, allowing for the sustained production of proteins that promote tissue healing. In a diabetic wound model, the engineered ASCs demonstrated superior wound healing efficacy compared to wild-type ASCs. This study suggests that lipid nanoparticles can be an effective platform for enhancing the protein generation ability of ASCs, advancing the development of ASC-based cell therapies. [Extracted from the article] |