| Abstrakt: |
Researchers at Jiaxing University in China have developed a dual-targeted metal ion network hydrogel scaffold that promotes the integrated repair of tendon-bone interfaces. The scaffold is constructed using peptide-modified zeolitic imidazolate framework-8 (LZIF-8) and magnesium metal-organic framework (WMg-MOF), which release zinc ions to enhance collagen secretion and magnesium ions to induce cell differentiation, respectively. This scaffold has the potential to facilitate synchronized multitissue regeneration at the compromised tendon-bone interface, offering promising prospects for its application in the reconstruction of gradient structures. The research has been peer-reviewed and published in ACS Applied Materials & Interfaces. [Extracted from the article] |
