| Autor: |
Nehra, Monika, Rohilla, Anjali, Beniwal, Nisha, Dilbaghi, Neeraj, Kumar, Rajesh, Kumar, Sandeep |
| Předmět: |
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| Zdroj: |
Engineering Proceedings; 2023, Vol. 35 Issue 1, p30, 7p |
| Abstrakt: |
The contamination of water and food with antibiotics residues poses a severe risk to human health and aquatic environments. The excessive and uncontrolled use of antibiotics is one of the major causes of their presence in the environment. Their continuous consumption willingly or un-willingly can result in severe health issues such as allergy, headache, hypertension, muscle pain, and hormonal dysfunction. Beside these, the development of antimicrobial resistance (AMR) can make the situation more critical. Therefore, advanced analytical approaches over conventional techniques are required to detect antibiotic residues in a facile and cost-effective manner. The present work deals with the design of fluorescent nanostructures as sensing probes for the detection of ciprofloxacin. Here, we have synthesized NH2-MIL-53(Al) using a hydrothermal approach. This fluorescent metal–organic framework (MOF) was further combined with molecular imprinted polymers (MIPs) for the selective and specific detection of ciprofloxacin in aqueous solutions. The use of MIPs over other biomolecules (such as antibody, enzymes, and others) is highly promising as it avoids any kind of pre-treatment of the sample. The MIP@NH2-MIL-53(Al) nanostructure formation is confirmed by performing different characterization techniques involving both spectroscopy and microscopy. The performance of the developed fluorescent composite promotes its applicability for the highly sensitive and specific detection of ciprofloxacin in practical applications. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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