| Abstrakt: |
Aedes aegypti is a vector that causes major public health problems because it is capable of transmitting dengue virus (DENV1-4), yellow fever, Zika, and chikungunya, and is resistant to chemical insecticides. These properties are driving research into new control methods, such as biological agents and plant oils. In this context, nanomaterials such as zinc oxide quantum dots (ZnO QD), which have great potential for biomedical sciences due to their bactericidal and antiviral activity, could be a viable alternative and need to be tested. Therefore, the aim of this study was to investigate the larvicidal potential of zinc oxide quantum dots on immature forms of Ae. aegypti. The morphological and structural characteristics of ZnO QD were analyzed using dynamic light scattering (DLS), field emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD), and high-resolution transmission electron microscopy (HRTEM). (HRTEM). Mortality bioassays were performed with Ae. aegypti by exposing third and fourth instar larvae to different concentrations of ZnO QD. The concentrations of 22 and 29 mg/mL resulted in 100% mortality of larvae after 24 h, the intermediate concentrations (7 and 14 mg/mL) were 33.75% and 72.5% lethal, respectively, while the concentrations of 0.01, 0.03, 0.05, 0.07, 0.11, and 3 mg/mL showed no mortality after 24 h. The results for LC 50 and LC 90 were 10.10 mg/mL and the 23.94 mg/mL, respectively. Thus, we have experimentally demonstrated that zinc oxide quantum dots can be an alternative for the control of Ae. aegypti, the major vector of arbovirus in the Americas. [ABSTRACT FROM AUTHOR] |
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