Autor: |
Gidey, Kidu, Aregawi, Solomon Girmay, Hailu, Berhane Yohannes, Asgedom, Solomon Weldegebreal, Niriayo, Yirga Legesse |
Předmět: |
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Zdroj: |
Infection & Drug Resistance; Jan2024, Vol. 17, p119-130, 12p |
Abstrakt: |
Objectives: This study aimed to evaluate the prevalence of antimicrobial use-related problems and risk factors among hospitalized pediatric patients.Materials and Methods: A hospital-based prospective observational study was conducted in Ayder comprehensive specialized hospital (ACSH) in the Tigray region, Ethiopia. The participants of the study were pediatric patients aged ≤ 15 years who were admitted with a diagnosis of infectious disease between September 2019 and November 2019.Results: A total of 232 pediatric patients were included in the study. Of these, 59.5% of the patients were male and the mean age (SD) of the patients was 5.8 (5.2) years. Of the 232 patients surveyed, a total of 177 antimicrobial use-related problems were identified. One or more antimicrobial use-related problems have occurred in more than half of the patients (53.9%). The commonest antimicrobial use problems were unnecessary antimicrobial therapy (22.8%) followed by need additional antimicrobial therapy (16.4%). In a multivariate logistic regression model, patients with comorbidities (Adjusted odds ratio (AOR): 1.84, 95% confidence interval (CI): 1.04– 3.27) and hospital stays exceeding one week (AOR=1.88, 95% CI: 1.08– 3.26) were predictors of antimicrobial use-related problems.Conclusion: Antimicrobial use-related problems were found in a significant proportion of pediatric patients. Addressing these issues necessitates collaborative efforts, emphasizing targeted education, strengthened antimicrobial stewardship, ensuring responsible antimicrobial use and enhancing pediatric care. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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