The efficacy and safety of non‐surgical treatment of diabetic foot wound infections and ulcers: A systemic review and meta‐analysis.

Autor:	Cai, Xuchao, Fang, Xin, Wu, Linjun, Meng, Xiaohu
Předmět:	TREATMENT of diabetic foot WOUND healing ONLINE information services MEDICAL databases META-analysis CONFIDENCE intervals MEDICAL information storage & retrieval systems WOUND infections SYSTEMATIC reviews DIABETIC foot TREATMENT effectiveness DESCRIPTIVE statistics RESEARCH funding AMPUTATION MEDLINE PATIENT safety WOUND care
Zdroj:	International Wound Journal; Feb2024, Vol. 21 Issue 2, p1-7, 7p
Abstrakt:	This meta‐analysis evaluates the efficacy and safety of non‐surgical treatments for diabetic foot ulcers and infections. After a rigorous literature review, seven studies were selected for detailed analysis. The findings demonstrate that non‐surgical treatments significantly reduce wound infection rates (standardized mean difference [SMD] = −15.15, 95% confidence interval [CI]: [−19.05, −11.25], p < 0.01) compared to surgical methods. Ulcer healing rates were found to be comparable between non‐surgical and surgical approaches (SMD = 0.07, 95% CI: [−0.38, 0.51], p = 0.15). Importantly, the rate of amputations within 6 months post‐treatment was significantly lower in the non‐surgical group (risk ratio [RR] = 0.19, 95% CI: [0.09, 0.41], p < 0.01). Additionally, a lower mortality rate was observed in patients treated non‐surgically (RR = 0.28, 95% CI: [0.13, 0.59], p < 0.01). These results affirm the effectiveness and safety of non‐surgical interventions in managing diabetic foot ulcers, suggesting that they should be considered a viable option in diabetic foot care. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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