| Autor: |
Verneker, Aishwarya K., Anu, Arava, N. R., Namrata, H. V., Raghavendra |
| Předmět: |
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| Zdroj: |
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2024, Vol. 15 Issue 1, p653-661, 9p |
| Abstrakt: |
Background: The Non-Hodgkin Lymphoma (NHL) are a heterogeneous group of lymphoproliferative malignancies, with distinct causes and shows distinctive patterns of behaviour and response to treatment consists of many subtypes, each with distinct epidemiology, aetiology, morphology, immunophenotypic, and clinical features. The present study was conducted with the aim of investigating the epidemiology of various subtype of NHL by using immunohistochemistry. Materials and methods: This prospective observational study was conducted in the department of pathology, Kidwai memorial institute of oncology, Bengaluru between the periods of November 2019 to May 2021. The epidemiology and various immunomorphological subtypes of Non-Hodgkin Lymphoma were studied. All de novo cases clinically suspected of NHL sample received in the department of pathology were included in the study. Clinical details and patients' history was recorded and immunohistochemistry staining was done. Result: We had a total of 136 cases of lymphoma out of which 56 cases were of Hodgkin lymphoma and 80 cases were of non-Hodgkin lymphoma. Mean age was 51.96 ± 17.17 years, with male majority including 46 males (57.5%). Most commonly we had B-cell type of NHL in 65 cases (81.2%) followed by T-cell in 13 cases (16.2%) and NK/T - cell in 1 case (1.25 %). Conclusion: We found that NHL cases were common in 5th decade with male predominance, with most common involvement in cervical lymph nodes. We conclude that a detailed clinical and histopathological evaluation of NHL cases is important for better patient management and prognosis. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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