DIAGNOSTIC VALUE OF C - REACTIVE PROTEIN (CRP) BY SEMIQUANTITATIVE METHOD IN PREDICTING OCCULT SERIOUS BACTERIAL INFECTION IN FEBRILE CHILDREN BETWEEN 1-36 MONTHS OF AGE.

Autor: S., Chithra, Reddy, Thota Chakradhar, S., Kirubakaran
Předmět:
Zdroj: Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2024, Vol. 15 Issue 1, p456-465, 10p
Abstrakt: Background: Fever is a common manifestation of infectious diseases but is not predictive of severity. Many common viral and bacterial infections are usually benign in normal hosts and respond well to appropriate antimicrobial or supportive therapy. Objective: To evaluate The diagnostic value of C - reactive protein (CRP) by semiquantitative method in predicting occult serious bacterial infection in febrile children between 1-36 months of age. Methods: This descriptive study was conducted at Institute of Child Health and Hospital for Children, Egmore, Chennai. Outpatient and Inpatient Departments/Wards. Results: WBC =15000 was observed in 9 cases of children who had SBI giving rise to sensitivity of 30%,97 children who did not have SBI have WBC <15000 giving a specificity of 88%. ESR = 15mm was observed in16 cases of children who had SBI giving rise to sensitivity of 53%, 94 children who did not have SBI have ESR<15mm giving a specificity of 85%. ANC =10000 was observed in 9 cases of children who had SBI giving rise to sensitivity of 30%, 104 children who did not have SBI have ANC <10000 giving a specificity of 95%. CRP=6mg/dl was observed in 23 cases of children who had SBI giving rise to sensitivity of 77%, 103 children who did not have SBI have CRP<6mg/dl giving a specificity of 94%. Conclusions: CRP is considered to be better predictive test than total white blood cell count and absolute neutrophil count. CRP and ANC or CRP, ANC &WBC combination is more useful than isolated CRP concentration. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index