Interleukin-2 production and response to exogenous interleukin-2 in a patient with the acquired immune deficiency syndrome (AIDS).

Autor: Hauser, G. J., Bino, Tamar, Rosenberg, H., Zakuth, Vera, Geller, E., Spirer, Z.
Předmět:
Zdroj: Clinical & Experimental Immunology; Apr1984, Vol. 56 Issue 1, p14-17, 4p
Abstrakt: The ability of lymphocytes from a patient suffering from the acquired immune deficiency syndrome (AIDS) to produce interleukin-2 (IL-2) was found to be comparable to that of his healthy sex partner and to that of a normal control. Addition of exogenous IL-2 to lymphocyte cultures did not improve the poor mitogen response to phytohaemagglutinin in this patient. Our data suggest that the underlying defect in this AIDS patient is due to an IL-2 receptor defect. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index