| Abstrakt: |
A recent report from the Salk Institute for Biological Studies in La Jolla, California discusses the role of the receptor tyrosine kinase Tyro3 in the development of glutamatergic synapses in the neocortex, hippocampus, and striatum. The researchers found that Tyro3 promotes the maturation of these synapses by driving the translocation of GluA2 AMPA receptor subunits to the plasma membrane. In the absence of Tyro3, synapses remained immature and mice displayed enhanced learning abilities in spatial recognition and fear-conditioning tasks. This research provides valuable insights into the mechanisms underlying synaptic development and function. [Extracted from the article] |
