| Autor: |
Muehling, Jakob, Fröba-Pohl, Alexandra, Muensterer, Oliver J., von Schweinitz, Dietrich, Kappler, Roland |
| Předmět: |
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| Zdroj: |
European Journal of Pediatric Surgery; Feb2024, Vol. 34 Issue 1, p69-77, 9p |
| Abstrakt: |
This article discusses a study on the expression of the BCL-2 gene in neuroblastoma (NB) patients. The study found that BCL-2 was expressed in all tumor samples, with higher expression levels associated with less severe disease and female patients. However, there was no correlation between BCL-2 expression and outcome or survival. The study also examined the correlation between BCL-2 and other genes, such as MYCN, and found no significant associations. The authors suggest that while BCL-2 may have potential for targeted therapy, its use as a diagnostic or prognostic marker in NB is limited and further research is needed. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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