| Autor: |
Wang, Xuan, Li, Jianlong, Du, Haifang, Liang, Weihong, Luo, Cheng, Wu, Yunshan, Liu, Bo |
| Předmět: |
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| Zdroj: |
Chemical Communications; 2/28/2024, Vol. 60 Issue 17, p2401-2404, 4p |
| Abstrakt: |
Herein, we report a new synthetic route to 1,4-epoxy-2-aryltetrahydro-1-benzazepine derivatives with high efficiency, namely the Rh(III)-catalyzed C–H allylation of nitrones with allyl precursors, followed by subsequent intramolecular 1,3-dipolar cycloaddition, to deliver the title compounds. This reaction is regio- and stereo-selective, generating the cis-isomer with a broad substrate scope and good functional group tolerance. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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