Risk of tuberculosis after endoscopic resection and gastrectomy in gastric cancer: nationwide population-based matched cohort study.
| Autor: | Khil, Hye Sung, Choi, Sue In, Kim, Byung-Keun, Lee, Eun Joo, Lee, Sang Yeub, Kim, Ji Hyun, Jung, Won Jai |
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| Předmět: |
STOMACH tumors
CHRONIC kidney failure CONFIDENCE intervals LOG-rank test TIME GASTRECTOMY RISK assessment DESCRIPTIVE statistics KAPLAN-Meier estimator CHI-squared test OBSTRUCTIVE lung diseases ENDOSCOPIC gastrointestinal surgery DATA analysis software LOGISTIC regression analysis LONGITUDINAL method PROBABILITY theory PROPORTIONAL hazards models |
| Zdroj: | Surgical Endoscopy & Other Interventional Techniques; Mar2024, Vol. 38 Issue 3, p1358-1366, 9p |
| Abstrakt: | Background: This study aimed to investigate the association between gastrectomy and endoscopic resection for gastric cancer and the subsequent tuberculosis incidence. Methods: We conducted a nationwide matched cohort study using data from the Korea National Health Insurance Service from 2013 to 2019. We created two cohorts: patients who underwent gastrectomy and those who had endoscopic resection. Each patient was matched 1:1 with an unexposed individual based on index year, age, sex, income, and various comorbidities. The primary outcome was the incidence of tuberculosis during the follow-up period. Results: Our study comprised 90,886 gastrectomy patients and 46,759 endoscopic resection patients. The tuberculosis incidence was significantly higher in the gastrectomy group compared to its matched non-gastrectomy group (IRR 1.69, 95% CI 1.43–1.99, p <.001). In contrast, there was no significant difference in tuberculosis incidence between the endoscopic resection group and its matched non-resection group (IRR 0.95, 95% CI 0.75–1.19, p = 0.627). The Kaplan–Meier cumulative incidence also did not differ between the two groups. However, tuberculosis incidence significantly increased in the first year after endoscopic resection. Conclusion: Gastrectomy for gastric cancer is associated with a higher incidence of subsequent tuberculosis, while no significant association was observed for endoscopic resection. However, tuberculosis incidence increases significantly during the first year after endoscopic resection. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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