| Autor: |
Fabrikov, Dmitri, Varga, Ágnes Timea, García, María Carmen Vargas, Bélteky, Péter, Kozma, Gábor, Kónya, Zoltán, López Martínez, Josefa L., Barroso, Fernando, Sánchez-Muros, María José |
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| Zdroj: |
Environmental Science & Pollution Research; Feb2024, Vol. 31 Issue 9, p13673-13687, 15p |
| Abstrakt: |
Regulation of antibiotic use in aquaculture calls for the emergence of more sustainable alternative treatments. Tea polyphenols (GTE), particularly epigallocatechin gallate (EGCG), have various biological activities. However, tea polyphenols are susceptible to degradation. In this work, EGCG and GTE were encapsulated in zein nanoparticles (ZNP) stabilized with alginate (ALG) and chitosan (CS) to reduce the degradation effect. ALG-coated ZNP and ALG/CS-coated ZNP encapsulating EGCG or GTE were obtained with a hydrodynamic size of less than 300 nm, an absolute ζ-potential value >30 mV, and an encapsulation efficiency greater than 75%. The antioxidant capacity of the encapsulated substances, although lower than that of the free ones, maintained high levels. On the other hand, the evaluation of antimicrobial activity showed greater efficiency in terms of growth inhibition for ALG/CS-ZNP formulations, with average overall values of around 60%, reaching an inhibition of more than 90% for Photobacterium damselae. These results support encapsulation as a good strategy for tea polyphenols, as it allows maintaining significant levels of antioxidant activity and increasing the potential for antimicrobial activity, in addition to increasing protection against sources of degradation. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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