Autor: |
Doddi, Akshith, Abbasi, Aisha, Ramesh, Ambika, Moursy, Safa, Sakhuja, Ankit, Shawwa, Khaled |
Předmět: |
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Zdroj: |
Journal of Intensive Care Medicine; Apr2024, Vol. 39 Issue 4, p387-394, 8p |
Abstrakt: |
Purpose: We investigated the impact of blood warmer use on hypotensive episodes in patients with acute kidney injury (AKI) receiving continuous kidney replacement therapy (CKRT). Materials and Methods: We included patients with AKI undergoing CKRT between January 1, 2012, and January 1, 2021, at a tertiary academic hospital. Hypotensive episodes were defined as mean arterial pressure (MAP) <60 mm Hg or a decrease in MAP by ≥10 mm Hg, systolic blood pressure (SBP) < 90 mm Hg or a decrease in SBP by ≥20 mm Hg, or increased vasopressor requirement. These were analyzed by Poisson regression with repeated-measures analysis of variance using generalized estimation equation. Results: There were 669 patients with AKI that required CKRT. Use of blood warmer on first day of CKRT was in 324 (48%) patients. Incidence rate ratio of hypotensive episodes during the first 24-h of CKRT in patients where a blood warmer was used was 1.06 (95% confidence interval [CI]: 0.98-1.13) compared to those where blood warmer was not used. This did not change in adjusted model. Overall, the within-subject effect of temperature on hypotensive episodes showed that higher temperature was associated with fewer episodes (0.94, 95% CI: 0.9-0.99 per 10 degrees increase, P =.007). Conclusion: Blood rewarming was not associated with hypotensive episodes during CKRT. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
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