BIRADS, Cytopathology and Histopathological Approach for Diagnosis of Breast masses in Erbil, A comparative Study.

Autor: Mustafa, Shna A., Jawhar, Nazar, Jalal, Jalal Ali, Khoshnaw, Dlovan S.
Předmět:
Zdroj: Medical Journal of Tikrit; 2022, Vol. 28 Issue 2, p28-42, 15p
Abstrakt: Background: Breast masses are the most common surgical problems among females; that is why their management requires an efficient and accurate evaluation using the least invasive and most accurate methods with a minimal patient's discomfort. Objectives: To determine the reliability and application of sonographic BIRADS lexicon in comparison with Fine needle aspiration cytology and Core needle biopsy results in order to differentiate benign from malignant breast masses. Also to determine the accuracy of FNAC and CNB in diagnosis of breast masses, including the sensitivity, specificity, positive and negative predictive values of both techniques in Erbil city and to compare the results of this study with those of others. Materials and Methods: This is a crosssectional study that was conducted on 132 female patients with breast masses who attended the breast cancer unit in Erbil at Rizgari Teaching Hospital, Maternity Teaching Hospital and some private clinics in a period spanning from 15 th July 2012 to 15th February 2013. After being detected sonographically, sonographic guided fine needle aspiration cytology (FNAC) and core needle biopsy (CNB) of breast masses were performed. Masses were classified according to the sonographic BIRADS lexicon, FNAC and CNB. Pathological results were compared with sonographic features. Results: Hypoechoic breast mass with axillary lymph nodes had shown highest presentation on BIRADS classification (30 samples of FNAC) in which most of them (70%) were malignant C5, while on CNB irregular hypoechoic mass had the highest presentation 29 samples were (79.3%) malignant B5. BIRADS, FNAC comparison had a high sensitivity of (97.5%) and negative predictive value of (92.8%). However, this study revealed a lower FNAC specificity (62.2%) and positive predictive value (73.6%). In the same line, CNB sensitivity and negative predictive value were high 95.5% and 92.6% respectively while the specificity and positive predictive value were low (59.5% and 71.7%). Conclusions: The BIRADS classification revealed that the highest frequencies of breast masses were among U5 (highly suspicious of malignancy) and U4 (suspicious of malignancy). Ultrasonic morphologic grading revealed that less than 30% of irregular outline masses of breast masses with axillary lymph nodes were benign masses and the reverse is true for those with well-defined masses or parenchymal changes. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index