| Autor: |
Gao, Jiale, Gu, Xiaodong, Pang, Minghui, Zhang, Hong, Lian, Yugui, Zhou, Lei, Feng, Bo, Wang, Guiying, Zhang, Zhicao, Huang, He, Xiao, Gang, Han, Fanghai, Li, Xinxiang, Zhou, Xiaojun, Wang, Quan, Liu, Qian, Deng, Haijun, Wang, Zhenjun, Song, Wu, Wei, Zhengqiang |
| Předmět: |
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| Zdroj: |
British Journal of Surgery; Jan2024, Vol. 111 Issue 1, p1-8, 8p |
| Abstrakt: |
Background: Right hemicolectomy is the standard treatment for right-sided colon cancer. There is variation in the technical aspects of performing right hemicolectomy as well as in short-term outcomes. It is therefore necessary to explore best clinical practice following right hemicolectomy in expert centres. Methods: This snapshot study of right hemicolectomy for colon cancer in China was a prospective, multicentre cohort study in which 52 tertiary hospitals participated. Eligible patients with stage I–III right-sided colon cancer who underwent elective right hemicolectomy were consecutively enrolled in all centres over 10 months. The primary endpoint was the incidence of postoperative 30-day anastomotic leak. Results: Of the 1854 patients, 89.9 per cent underwent laparoscopic surgery and 52.3 per cent underwent D3 lymph node dissection. The overall 30-day morbidity and mortality were 11.7 and 0.2 per cent, respectively. The 30-day anastomotic leak rate was 1.4 per cent. In multivariate analysis, ASA grade > II (P < 0.001), intraoperative blood loss > 50 ml (P = 0.044) and D3 lymph node dissection (P = 0.008) were identified as independent risk factors for postoperative morbidity. Extracorporeal side-to-side anastomosis (P = 0.031), intraoperative blood loss > 50 ml (P = 0.004) and neoadjuvant chemotherapy (P = 0.004) were identified as independent risk factors for anastomotic leak. Conclusion: In high-volume expert centres in China, laparoscopic resection with D3 lymph node dissection was performed in most patients with right-sided colon cancer, and overall postoperative morbidity and mortality was low. Further studies are needed to explore the optimal technique for right hemicolectomy in order to improve outcomes further. This snapshot study was a prospective, multicentre, cohort study to explore the clinical practise and outcome of right hemicolectomy in China. In high-volume expert centres, laparoscopic resection with D3 lymph node dissection was performed in most patients with right-sided colon cancer, and overall postoperative morbidity and mortality were low. The risk factors of morbidity and anastomotic leak were identified. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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