Atypical porphyria cutanea tarda mimicking morphea.

Autor: Guimarães, Maria J., Nogueira, Carlos M., Cerqueira, Catarina, Lopes, Ana G., Brito, Celeste, Araújo, Catarina
Předmět:
Zdroj: Portuguese Journal of Dermatology & Venereology; Oct-Dec2023, Vol. 81 Issue 4, p293-294, 2p
Abstrakt: This case study, published in the Portuguese Journal of Dermatology & Venereology, describes a 65-year-old man with a history of alcohol abuse who presented with cicatricial alopecia and whitish sclerotic plaques on his upper chest. The patient also had a hyperpigmented area of hypertrichosis on his scalp. Laboratory evaluation revealed iron overload and elevated transaminases. A cutaneous biopsy confirmed the diagnosis of morphea, but one month later, the patient developed blistering and crusting of the forearms, and urine analysis revealed increased uroporphyrins, indicating a diagnosis of porphyria cutanea tarda (PCT). The patient was treated with phlebotomies and advised to practice photoprotection and alcohol withdrawal. The study highlights the challenge of distinguishing between morphea and sclerodermiform PCT, especially when faced with therapy failure. [Extracted from the article]
Databáze: Complementary Index