Researchers from University of Picardie Jules Verne Report Recent Findings in Acute Myeloid Leukemia (Stim2 Is Involved In the Regulation of Apoptosis and the Cell Cycle In Normal and Malignant Monocytic Cells).

Předmět:	CELL cycle regulation ACUTE myeloid leukemia CANCER cells RESEARCH personnel TUMOR suppressor proteins TUMOR antigens
Zdroj:	Hematology Week; 2/19/2024, p1230-1230, 1p
Abstrakt:	Researchers from the University of Picardie Jules Verne in France have published a new report on acute myeloid leukemia (AML). The study focuses on the role of stromal interaction molecule 2 (STIM2) in AML with monocytic differentiation. The researchers found that STIM2 is highly expressed in AML and negatively correlated with overall survival. They also discovered that STIM2 plays a role in cell proliferation, differentiation, and survival in leukemic cell lines with monocytic potential and in normal hematopoietic stem cells. The study concludes that STIM2 is a new regulator of genomic stability and the p53 response in normal and malignant monocytic cells. [Extracted from the article]
Databáze:	Complementary Index
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