Abstrakt: |
A recent study conducted by researchers at the University of Trento in Italy explores protein biomarkers for the diagnosis and prognosis of Amyotrophic Lateral Sclerosis (ALS), a neurodegenerative disease. ALS is a complex disease with genetic and phenotypic variations, making it challenging to develop effective treatments. The study discusses various biomarkers that have been tested in multicenter studies, including neurofilaments, neuroinflammatory-related proteins, p75ECD, p-Tau/t-Tau, and UCHL1. The researchers also explore the potential of muscle proteins and extracellular vesicles as biomarkers. This research provides valuable insights into the search for markers that can aid in the diagnosis and treatment of ALS. [Extracted from the article] |