CAR T cells show promise against age-related diseases in mice.

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Zdroj: Obesity, Fitness & Wellness Week; 2/20/2024, p155-155, 1p
Abstrakt: A recent study led by Memorial Sloan Kettering Cancer Center and Cold Spring Harbor Laboratory has found that chimeric antigen receptor (CAR) T cells, which have been successful in treating blood cancers, may also hold promise for treating age-related diseases caused by the accumulation of senescent cells. The study showed that an infusion of CAR T cells targeting senescent cells improved metabolic function in older mice and mice with a high-fat diet. The treatment also prevented metabolic decline in young, healthy mice. Further research is needed to determine if this approach can extend lifespan and improve overall health. [Extracted from the article]
Databáze: Complementary Index