Detection of Rotavirus in Respiratory Specimens From Bangladeshi Children Aged <2 Years Hospitalized for Acute Gastroenteritis.

Autor: Satter, Syed Moinuddin, Katz, Eric, Hossain, Mohammad Enayet, Fariha, Farzana, Talha, Muhammad, Smart, Sarah L, Bowen, Michael D, Rahman, Mustafizur, Parashar, Umesh D, Cortese, Margaret M
Předmět:
Zdroj: Journal of Infectious Diseases; 2/15/2024, Vol. 229 Issue 2, p457-461, 5p
Abstrakt: To examine the potential for respiratory transmission of rotavirus, we systematically assessed if rotavirus RNA is detectable by real-time quantitative reverse transcription-polymerase chain reaction from nasal and oropharyngeal swab specimens of Bangladeshi children with acute rotavirus gastroenteritis. Forehead swabs were collected to assess skin contamination. Among 399 children aged <2 years hospitalized for gastroenteritis during peak rotavirus season, rotavirus RNA was detected in stool, oral, nasal and forehead swab specimens of 354 (89%). A subset was genotyped; genotype was concordant within a child's specimen set and several different genotypes were detected across children. These findings support possible respiratory transmission of rotavirus and warrant further investigation. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index