Exploring the Phytochemical Composition and Pharmacological Activities of Cerbera manghas and C. odollam: A Comprehensive Review.

Autor: Ilmiawati, Auliya, Mujahidah, Ummahatul, Arinana, Batubara, Irmanida, Nurcholis, Waras
Předmět:
Zdroj: Tropical Journal of Natural Product Research; Jan2024, Vol. 8 Issue 1, p5715-5726, 12p
Abstrakt: Cerbera manghas and C. odollam, often perceived as similar species, exhibit distinct physical characteristics and phylogenetic classifications. Despite their reputation as poisonous plants, both species have diverse benefits and are potential sources of pharmacological compounds. This report comprehensively summarizes the compounds identified within the genus Cerbera, coupled with reported bioactivities. Over 100 compounds, including phenolics, flavonoids, terpenoids, and steroids, have been isolated from C. manghas and C. odollam. Cardiac glycosides (steroids) are the predominant compounds in these species and demonstrate robust cytotoxic activity. Furthermore, both plants show promise as antioxidants and antimicrobial agents, and exhibit insecticidal, termiticidal, and larvicidal properties. This review consolidates the current understanding of the phytochemical and pharmacological attributes of C. manghas and C. odollam. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index