Abstrakt: |
A recent study conducted by researchers at the University of Chile explored the use of beeswax oleogels as oral delivery vehicles for curcuminoids. The researchers formulated oleogels with avocado, sunflower, and linseed oils and found that the incorporation of curcumin into the oleogel matrix delayed the formation of peroxides and conjugated trienes. The bioaccessibility of curcuminoids remained high in all oleogels, but the release of fatty acids during gastrointestinal digestion was reduced. The study also found that the intestinal absorption of curcumin was higher from the digested oleogels compared to unstructured oils, and the oleogels exhibited anti-inflammatory activity. Overall, the findings suggest that beeswax-based oleogels could be promising vehicles for the oral delivery of curcuminoids. [Extracted from the article] |