Comparison of Invasive and Non-Invasive Mechanical Ventilation in COVID-19 Patients Followed with Respiratory Failure.

Autor: Moralar, Döndü Genç, Türkmen, Ülkü Aygen, Çelik, Osman, Uluç, Aleaddin, Şahin, Serpil Şehirlioğlu
Předmět:
Zdroj: Comprehensive Medicine; Jan2024, Vol. 16 Issue 1, p32-38, 7p
Abstrakt: Objective: The most important complication associated with coronavirus disease-19 (COVID-19) is respiratory failure, which requires mechanical ventilation. The aim of our study is to evaluate the effectiveness of the use of invasive and non-invasive mechanical ventilation (NIV) on oxygenation in patients with COVID-19 who had respiratory failure and needed ventilation support. Materials and Methods: According to the ventilation support used, the patients were divided into two groups: Those for whom NIV was initially preferred (n=48) and those who were initially intubated and received invasive mechanical ventilation (n=50). Arterial blood gas analyzes of the patients were evaluated. The changes in oxygenation and ventilation, the incidence of complications such as hypotension and hypertension, and mortality rates were compared. Results: The partial arterial oxygen pressure (PaO2) values were similar during the follow-up of the patients who were initiated on treatment with NIV and those who were initiated on treatment with invasive mechanical ventilation. However, the survival rate was higher in the patients who were initiated on treatment with non-invasive mechanical ventilation. It was remarkable that the partial arterial carbon dioxide pressure value was higher in the invasive mechanical ventilation group than in the NIV group. The incidence of complications such as hypotension or hypertension was less in the non-invasive mechanical ventilation group. Conclusion: Although PaO2 values are similar, it was found that the survival rate was higher and the complication rate was lower in the patients for whom NIV was preferred. Therefore, we think that NIV should be preferred as much as possible. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index