The Use of Fibrin Sealants in Reducing Postoperative Complications in Skull Base Surgery: A Systematic Review and Meta-Analysis.

Autor: Eberly, Hanel W., Rosi-Schumacher, Mattie, Sciscent, Bao Y., Truong, Nguyen M., King, Tonya S., Goldenberg, David, Goyal, Neerav
Předmět:
Zdroj: Journal of Neurological Surgery. Part B. Skull Base; 2024 Supplement, Vol. 85, pS1-S398, 398p
Abstrakt: This article, published in the Journal of Neurological Surgery, examines the use of fibrin sealants in reducing postoperative complications in skull base surgery. The study conducted a systematic review and meta-analysis of published studies that assessed patients who had undergone skull base surgery with the use of fibrin sealants. The results showed that patients who received fibrin sealants had a lower incidence of postoperative cerebrospinal fluid (CSF) leak and drain placement compared to those who did not receive fibrin sealants. However, there was no significant difference in the incidence of revision surgery or infection between the two groups. Overall, the findings suggest that fibrin sealants may be effective in reducing CSF leaks and related complications in skull base surgery. [Extracted from the article]
Databáze: Complementary Index