| Autor: |
Akarsu, Mesut, Dolu, Suleyman, Harputluoglu, Murat, Yilmaz, Sezai, Akyildiz, Murat, Gencdal, Genco, Polat, Kamil Yalcin, Dincer, Dinc, Adanir, Haydar, Turan, Ilker, Gunsar, Fulya, Karasu, Zeki, Gokcan, Hale, Karademir, Sedat, Kabacam, Gokhan, Kayhan, Meral Akdogan, Kiyici, Murat, Gulsen, Murat Taner, Balaban, Yasemin, Dogrul, Ahmet Bulent |
| Předmět: |
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| Zdroj: |
Hepatology Forum; Jan2024, Vol. 5 Issue 1, p3-6, 4p |
| Abstrakt: |
Background and Aim: This study aimed to identify the indications for liver transplantation (LT) based on underlying etiology and to characterize the patients who underwent LT. Materials and Methods: We conducted a multicenter cross-sectional observational study across 11 tertiary centers in Turkiye from 2010 to 2020. The study included 5,080 adult patients. Results: The mean age of patients was 50.3±15.2 years, with a predominance of female patients (70%). Chronic viral hepatitis (46%) was the leading etiological factor, with Hepatitis B virus infection at 35%, followed by cryptogenic cirrhosis (24%), Hepatitis C virus infection (8%), and alcohol-related liver disease (ALD) (6%). Post-2015, there was a significant increase in both the number of liver transplants and the proportion of living donor liver transplants (p<0.001). A comparative analysis of patient characteristics before and after 2015 showed a significant decline in viral hepatitis-related LT (p<0.001), whereas fatty liver disease-related LT significantly increased (p<0.001). Conclusion: Chronic viral hepatitis continues to be the primary indication for LT in Turkiye. However, the proportions of non-alcoholic fatty liver disease (NAFLD) and ALD-related LT have seen an upward trend over the years. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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