Extracting Drug-Protein Relation from Literature Using Ensembles of Biomedical Transformers.

Autor: DAS, Avisha, Zhao LI, Qiang WEI, Jianfu LI, Liang-chin HUANG, Yan HU, Rongbin LI, Wenjin Jim ZHENG, Hua XU
Zdroj: Studies in Health Technology & Informatics; 2023, Vol. 310, p639-643, 5p
Abstrakt: Automatic extraction of relations between drugs/chemicals and proteins from ever-growing biomedical literature is required to build up-to-date knowledge bases in biomedicine. To promote the development of automated methods, BioCreative-VII organized a shared task - the DrugProt track, to recognize drug-protein entity relations from PubMed abstracts. We participated in the shared task and leveraged deep learning-based transformer models pre-trained on biomedical data to build ensemble approaches to automatically extract drug-protein relation from biomedical literature. On the main corpora of 10,750 abstracts, our best system obtained an F1-score of 77.60% (ranked 4th among 30 participating teams), and on the large-scale corpus of 2.4M documents, our system achieved micro-averaged F1-score of 77.32% (ranked 2nd among 9 system submissions). This demonstrates the effectiveness of domain-specific transformer models and ensemble approaches for automatic relation extraction from biomedical literature. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index