Primate-to-human retroviral transmission in Asia.
| Autor: | Jones-Engel, Lisa, Engel, Gregory A., Schillaci, Michael A., Rompis, Aida, Putra, Artha, Suaryana, Komang Gde, Fuentes, Agustin, Beer, Brigitte, Hicks, Sarah, White, Robert, Wilson, Brenda, Allan, Jonathan S. |
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| Předmět: |
RETROVIRUS diseases
INFECTIOUS disease transmission FOAMY viruses SIMIAN viruses MACAQUES SERUM POLYMERASE chain reaction PHYLOGENY ANIMAL diseases COMPARATIVE studies DNA EPIDEMIOLOGICAL research BIOLOGICAL evolution RESEARCH methodology MEDICAL cooperation PRIMATES RESEARCH RESEARCH funding RETROVIRUSES EVALUATION research |
| Zdroj: | Emerging Infectious Diseases; Jul2005, Vol. 11 Issue 7, p1028-1035, 8p, 3 Diagrams, 3 Charts |
| Abstrakt: | We describe the first reported transmission to a human of simian foamy virus (SFV) from a free-ranging population of nonhuman primates in Asia. The transmission of an exogenous retrovirus, SFV, from macaques (Macaca fascicularis) to a human at a monkey temple in Bali, Indonesia, was investigated with molecular and serologic techniques. Antibodies to SFV were detected by Western blotting of serum from 1 of 82 humans tested. SFV DNA was detected by nested polymerase chain reaction (PCR) from the blood of the same person. Cloning and sequencing of PCR products confirmed the virus's close phylogenetic relationship to SFV isolated from macaques at the same temple. This study raises concerns that persons who work at or live around monkey temples are at risk for infection with SFV. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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