Evaluation of American College of Radiology Ovarian‐Adnexal Reporting and Data System ultrasound to predict malignancy risk in adnexal lesions.

Autor:	Li, Ya, Shao, Guangrui, Wu, Mei, Zhang, Feixue, Zhang, Yuqing, Shao, Chunchun
Předmět:	MEDICAL radiology PREOPERATIVE care MEDICAL information storage & retrieval systems PREDICTIVE tests CONFIDENCE intervals RISK assessment T-test (Statistics) DESCRIPTIVE statistics SENSITIVITY & specificity (Statistics) DATA analysis software DIAGNOSTIC errors RECEIVER operating characteristic curves PRECANCEROUS conditions LONGITUDINAL method DISEASE risk factors
Zdroj:	Journal of Obstetrics & Gynaecology Research; Feb2024, Vol. 50 Issue 2, p225-232, 8p
Abstrakt:	Aims: To validate the diagnostic performance of Ovarian‐Adnexal Reporting and Data System (O‐RADS) ultrasound for preoperative adnexal lesions in an external center. The secondary aim was to evaluate the performance of a strategy test including O‐RADS ultrasound evaluation and subjective assessment of higher malignant risk lesions. Methods: One hundred thirty patients with 158 ovarian‐adnexal lesions were enrolled in the study. Each lesion was assigned an O‐RADS score after real‐time ultrasound examination by one experienced radiologist. A second subjective assessment by an expert was performed for O‐RADS 4 and O‐RADS 5 lesions. The histopathological diagnosis was used as the reference standard. Results: A total of 126 benign and 32 malignant adnexal masses were included in the study. The area under the receiver operating characteristic curve of O‐RADS ultrasound was 0.950, with a cutoff value > O‐RADS 3. The sensitivity, specificity, and negative and positive predictive values were 100% (95% confidence interval [CI], 0.867–1), 83.3% (95% CI, 0.754–0.892), 60.4% (95% CI, 0.460–0.732), and 100% (95% CI, 0.956–1), respectively. For the strategy test, the sensitivity, specificity, negative and positive predictive values were 100% (95% CI, 0.867–1), 92.1% (95% CI, 0.855–0.959), 76.2% (95% CI, 0.602–0.874), and 100% (95% CI, 0.960–1), respectively. In comparison with O‐RADS ultrasound, the specificity and negative predictive value of the strategy test were slightly higher (p < 0.05). Conclusions: Good diagnostic performance of the O‐RADS ultrasound in adnexal lesions can be achieved by experienced radiologists in clinical practice. A second subjective assessment of sonographic findings can be applied to O‐RADS 4 and 5 lesions. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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