| Autor: |
Francis, Jenelle M., Mowat, Freya M., Ludwig, Allison, Hicks, Jacqueline M., Pumphrey, Stephanie A. |
| Předmět: |
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| Zdroj: |
Veterinary Ophthalmology; Jan2024, Vol. 27 Issue 1, p70-78, 9p |
| Abstrakt: |
Objective: To evaluate the relationship between nuclear sclerosis (NS) and refractive error in companion dogs. Animals studied: One hundred and eighteen companion dogs. Procedures: Dogs were examined and found to be free of significant ocular abnormalities aside from NS. NS was graded from 0 (absent) to 3 (severe) using a scale developed by the investigators. Manual refraction was performed. The effect of NS grade on refractive error was measured using a linear mixed effects analysis adjusted for age. The proportion of eyes with >1.5 D myopia in each NS grade was evaluated using a chi‐square test. Visual impairment score (VIS) was obtained for a subset of dogs and compared against age, refractive error, and NS grade. Results: Age was strongly correlated with NS grade (p <.0001). Age‐adjusted analysis of NS grade relative to refraction showed a mild but not statistically significant increase in myopia with increasing NS grade, with eyes with grade 3 NS averaging 0.58–0.88 D greater myopia than eyes without NS. However, the myopia of >1.5 D was documented in 4/58 (6.9%) eyes with grade 0 NS, 12/91 (13.2%) eyes with grade 1 NS, 13/57 (22.8%) eyes with grade 2 NS, and 7/23 (30.4%) eyes with grade 3 NS. Risk of myopia >1.5 D was significantly associated with increasing NS grade (p =.02). VIS was associated weakly with refractive error, moderately with age, and significantly with NS grade. Conclusions: NS is associated with visual deficits in some dogs but is only weakly associated with myopia. More work is needed to characterize vision in aging dogs. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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