| Autor: |
Shanthi, Markabandhu, Perumal, Karuppaiah, Sivalingam, Soumya, Puhazhendhi, Arulmozhi, Kumar Mandali, Pavan, Ramesh, Subburethinam |
| Předmět: |
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| Zdroj: |
Synlett; Feb2024, Vol. 35 Issue 3, p313-318, 6p |
| Abstrakt: |
This article explores the significance of C-S bond formation in the synthesis of bioactive and pharmaceutical compounds, as well as polymeric compounds and organic materials. Traditional methods for forming C-S bonds rely on transition-metal-catalyzed reactions, which can be harsh. However, recent research has focused on transition-metal-free and photocatalyst-free methods using visible-light irradiation and electron donor-acceptor complexes. The article presents various strategies and optimization of reaction conditions for synthesizing pyrazole thioethers. The study demonstrates a photoinduced thiolation reaction of halopyrazolamines using thiophenol and a base, conducted at room temperature with blue LEDs. The yields of the thiolated compounds ranged from moderate to excellent, and UV-vis spectroscopy confirmed the formation of a π-π complex or a halogen bond. These findings provide insights into the reaction mechanism and offer a new approach to synthesizing thiolated compounds. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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