| Autor: |
Okumura, Shintaro, Takahashi, Teruki, Torii, Kaoru, Uozumi, Yasuhiro |
| Předmět: |
|
| Zdroj: |
Synlett; Feb2024, Vol. 35 Issue 3, p303-306, 4p |
| Abstrakt: |
This article discusses the development of a photocatalytic 1,4-addition reaction of aromatic aldehydes or ketones with electron-deficient olefins. The reaction proceeds through the generation of umpoled carbinol anions, which are formed through two successive one-electron reductions. The use of CO2 as an additive enhances the reaction, resulting in the formation of γ-substituted secondary or tertiary alcohols in yields of up to 92%. The findings of this study offer a new avenue in synthetic organic chemistry and provide an alternative to the ketyl Giese reaction. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
