A Metal‐Free KOtBu‐Mediated Protocol towards the Synthesis of Quinolines, Indenoquinolines and Acridines.

Autor: Satya Kishore, Pendyala, Gujjarappa, Raghuram, Jagdishbhai Patel, Mayur, Polina, Saibabu, Kishore Putta, V. P. Rama, Singh, Virender, Malakar, Chandi C., Pralhad Pujar, Prasad
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Zdroj: ChemistrySelect; 1/26/2024, Vol. 9 Issue 4, p1-6, 6p
Abstrakt: An expeditious strategy has been developed for the synthesis of diverse quinolines, indenoquinolines and acridines using KOtBu‐mediated reaction conditions. The designed process utilizes 2‐aminoaryl carbaldehydes/2‐aminoaryl ketones and methyl/methylene group containing ketones as readily available feedstock. The chemical transformation was affected at room temperature within a short duration of time to obtain diverse N‐heterocycles yields up to 92 %. The established process also exhibits considerable functional group tolerance with an operational simplicity. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index