Effects of a Primary Care Antimicrobial Stewardship Program on Meticillin-Resistant Staphylococcus aureus Strains across a Region of Catalunya (Spain) over 5 Years.

Autor: Jover-Sáenz, Alfredo, Ramírez-Hidalgo, María, Bellés Bellés, Alba, Ribes Murillo, Esther, Batlle Bosch, Meritxell, Ribé Miró, Anna, Mari López, Alba, Cayado Cabanillas, José, Piqué Palacín, Neus, Garrido-Calvo, Sònia, Ortiz Valls, Mireia, Gracia Vilas, María Isabel, Gros Navés, Laura, Javierre Caudevilla, María Jesús, Montull Navarro, Lidia, Bañeres Argiles, Cecilia, Vaqué Castilla, Pilar, Ichart Tomás, José Javier, Saura Codina, Mireia, Andreu Mayor, Ester
Předmět:
Zdroj: Antibiotics (2079-6382); Jan2024, Vol. 13 Issue 1, p92, 17p
Abstrakt: Primary care antimicrobial stewardship program (ASP) interventions can reduce the over-prescription of unnecessary antibiotics, but the impact on the reduction in bacterial resistance is less known, and there is a lack of available data. We implemented a prolonged educational counseling ASP in a large regional outpatient setting to assess its feasibility and effectiveness. Over a 5-year post-implementation period, which was compared to a pre-intervention period, a significant reduction in antibiotic prescriptions occurred, particularly those associated with greater harmful effects and resistance selection. There was also a decrease in methicillin-resistant Staphylococcus aureus (MRSA) strains and in their co-resistance to other antibiotics, particularly those with an ecological impact. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index