Mediators of the association between albuminuria and incident cancer: the PREVEND study.

Autor:	Luo, Li, Vart, Priya, Kieneker, Lyanne M, van der Vegt, Bert, Bakker, Stephan J L, Gruppen, Eke G, Casteleijn, Niek F, Boer, Rudolf A de, Suthahar, Navin, Bock, Geertruida H de, Aboumsallem, Joseph Pierre, Gansevoort, Ron T
Předmět:	ALBUMINURIA BRAIN natriuretic factor ENDOTHELIUM diseases URINARY tract infections
Zdroj:	Clinical Kidney Journal; Jan2024, Vol. 17 Issue 1, p1-5, 5p
Abstrakt:	This article examines the relationship between albuminuria (a marker of chronic kidney disease) and the occurrence of cancer. The study analyzes data from a Dutch population-based cohort and identifies potential factors that explain the connection between albuminuria and cancer. The researchers find that markers of systemic inflammation, oxidative stress, and kidney function partially mediate the association between albuminuria and overall cancer incidence. The study provides valuable insights into the mechanisms linking albuminuria and cancer, suggesting that inflammation may play a role in cancer development in individuals with albuminuria. Further research is needed to explore other potential factors and pathways. [Extracted from the article]
Databáze:	Complementary Index
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