Is prior bariatric surgery associated with poor COVID-19 outcomes? A systematic review and meta-analysis of case-control studies.
| Autor: | Xiang Gao, Pengzhou Li, Song Dai, Guohui Wang, Weizheng Li, Zhi Song, Liyong Zhu, Shaihong Zhu |
|---|---|
| Předmět: |
INTENSIVE care units
LENGTH of stay in hospitals ONLINE information services MEDICAL databases COVID-19 META-analysis CONFIDENCE intervals MEDICAL information storage & retrieval systems BARIATRIC surgery SYSTEMATIC reviews MORTALITY CASE-control method SEVERITY of illness index TREATMENT effectiveness ARTIFICIAL respiration COMPARATIVE studies HOSPITAL care RESEARCH funding HEMODIALYSIS ODDS ratio MEDLINE DATA analysis software |
| Zdroj: | Journal of Global Health; 2023, Vol. 13, p1-11, 11p |
| Abstrakt: | Background Obesity is an independent risk factor for severe coronavirus disease 2019 (COVID-19), but there is little evidence on whether prior bariatric surgery benefits the outcomes of patients with COVID-19. We aimed to summarize this relationship by conducting a systematic review and meta-analysis of current case-control studies. Methods We searched several electronic databases for case-control studies conducted between January 2020 and March 2022. We compared the rates of mortality, mechanical ventilation, intensive care unit (ICU) admission, dialysis, hospitalization, and length of hospital stay between COVID-19 patients with and without a history of bariatric surgery. Results We included six studies with 137 903 patients; 5270 (3.8%) had prior bariatric surgery, while 132 633 (96.2%) did not. COVID-19 patients with a history of bariatric surgery had significantly lower mortality (odds ratio (OR) = 0.42; 95% confidence interval (CI) = 0.23-0.74), ICU admission (OR=0.48; 95% CI=0.36-0.65), and mechanical ventilation rates than those with a history of non-bariatric surgery (OR=0.51; 95% CI=0.35-0.75). Conclusions Prior bariatric surgery was associated with a reduced risk of mortality and reduced severity of COVID-19 in patients with obesity compared to those with no prior bariatric surgery. Further large-sample prospective studies are needed to support these results. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
| Externí odkaz: |
|