| Abstrakt: |
This study investigated the potential of coronary sinus blood temperature to detect ventricular arrhythmias. A rapid-response, thermistor-tipped catheter placed in the coronary venous system of anesthetized dogs was used to record the blood temperature during periods of induced bradycardia, tachycardia, and ventricular fibrillation. A second catheter was used to measure blood temperature in the aortic arch during these same episodes. A pulsatile component of venous blood temperature, typically 40 m°C in amplitude, was well correlated with the cardiac cycle, while another, slightly larger, pulsatile component was well correlated with respiration. The cardiac component peaked during ventricular systole, and the respiratory component peaked during expiration. As compared with sinus rhythm, the cardiac signal diminished during tachycardia and tachycardia and nearly disappeared during asystole and ventricular fibrillation. The baseline component of venous blood temperature rose during periods of tachycardia and fibrillation, while respiration proved to bean important factor in the baseline temperatures. The presence of small, cyclic, thermal variations in the coronary venous system was verified, and the concept of measuring metabolic activity to assess ventricular function was substantiated. These studies show promise that this concept could be incorporated into medical devices that use these temperature signals for diagnosis of ventricular arrhythmias. [ABSTRACT FROM AUTHOR] |
Plný text