Research from Semmelweis University Provide New Insights into Cancer (The Role of TRPM7 in Oncogenesis).

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Zdroj: Cancer Weekly; 1/23/2024, p729-729, 1p
Abstrakt: A recent study conducted by researchers at Semmelweis University in Budapest, Hungary, explores the role of transient receptor potential melastatin-subfamily member 7 (TRPM7) channels in the development of cancer. The TRPM7 protein, which has both kinase activity and channel function, has been found to play a significant role in tumorigenesis and other tumor hallmarks such as proliferation, migration, invasion, and metastasis. The study suggests that targeting TRPM7 may hold promise for future tumor therapy. The research provides an up-to-date overview of the possible role of TRPM7 in various malignancies, including tumors of the nervous system, head and neck cancers, gastrointestinal tract neoplasms, lung cancer, breast cancer, and prostate cancer, among others. [Extracted from the article]
Databáze: Complementary Index